Retinoblastoma Binding Protein 8 (RBBP8) (Middle Region) Peptid
RBBP8
Reaktivität: Human
Wirt: Synthetic
BP, WB
Produktnummer ABIN982714
Kurzübersicht für Retinoblastoma Binding Protein 8 (RBBP8) (Middle Region) Peptid (ABIN982714)
Target
Retinoblastoma Binding Protein 8 (RBBP8)
Spezies
Human
Quelle
Synthetic
Applikation
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- Middle Region
-
Sequenz
- CQQKKEKRNW LPAQDTDSAT FHPTHQRIFG KLVFLPLRLV WKEVILRKIL
-
Produktmerkmale
- This is a synthetic peptide designed for use in combination with anti-RBBP8 Antibody(ARP50888_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Aufreinigung
- Purified
-
-
-
-
Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Rekonstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Konzentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Retinoblastoma Binding Protein 8 (RBBP8)
-
Hintergrund
-
RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Alias Symbols: CTIP, RIM, JWDS, SAE2, SCKL2
Protein Interaction Partner: BRCA1,LMO2,LMO4,ATM,BARD1,BRCA1,C17orf28,CTBP1,FXR2,IKZF1,IKZF3,LIMS1,LMO2,LMO4,PCNA,PIN1,RB1,RBBP8,RBL1,RBL2,SIAH1,SIAH2,TGIF2,WDYHV1,ATM,BARD1,BRCA1,C17orf28,CTBP1,FXR2,IKZF1,LIMS1,LMO4,Lmo2,PIN1,PRKDC,RB1,RBBP8,RBL1,RBL2,SIAH1,SIAH2,UBC,WDYHV1
Protein Size: 867 -
Molekulargewicht
- 98 kDa
-
Gen-ID
- 5932
-
NCBI Accession
- NM_203292, NP_976037
-
UniProt
- A6NKN2
Target
-
Sie sind hier:
